You're viewing 3 free preview questions for Biology SL — subscribe to unlock 68 more, plus the Full Question Bank, Mock Papers & Worksheets.Upgrade

Integration of Body Systems · Paper 2 — Free Biology SL Practice Questions

1MasterySAQ-SHomeostasis and feedback mechanisms5 marksPaper 2~8 min
A patient is admitted to hospital with severe dehydration following prolonged vomiting and diarrhoea. Blood analysis reveals that the sodium ion concentration in the plasma has risen from the normal range of 135135–145 mmol dm−3145\,\text{mmol dm}^{-3} to 158 mmol dm−3158\,\text{mmol dm}^{-3}. The patient's urine output is very low and has a high osmolality.
(a)
State the location of the osmoreceptors that detect this increase in plasma osmolality. [1 mark]
(b)
Explain how the coordinating centre and the effector respond to restore plasma osmolality toward normal. [2 marks]
(c)
A healthy adult has a plasma sodium concentration of 140 mmol dm−3140\,\text{mmol dm}^{-3} and produces 1.5 dm31.5\,\text{dm}^{3} of urine per day with a sodium concentration of 100 mmol dm−3100\,\text{mmol dm}^{-3}. Calculate the mass of sodium excreted per day in the urine. (Molar mass of sodium =23.0 g mol−1= 23.0\,\text{g mol}^{-1}) [2 marks]
diagram

Solutions

2ChallengeSAQ-LEndocrine and nervous system integration7 marksPaper 2~11 min

Data

Time — Blood pressure (mmHg) — Heart rate (bpm) — Plasma adrenaline (nmol L−1^{-1}) Resting — 120/80 — 72 — 0.3 2 min post-stimulation — 180/110 — 55 — 2.1 5 min post-stimulation — 175/108 — 56 — 2.0 The baroreceptor reflex arc: baroreceptors (aorta / carotid sinus) →\rightarrow afferent neurons →\rightarrow medulla oblongata →\rightarrow efferent parasympathetic (vagus nerve) and sympathetic pathways →\rightarrow heart and blood vessels.
A medical researcher investigates autonomic dysreflexia in a patient with a complete spinal cord transection at the T6 level. The researcher stimulates the patient's skin below the injury site and records the following
(a)
Calculate the percentage change in plasma adrenaline concentration from resting to the peak value. [2 marks]
(b)
Explain how the nervous system integrates with the endocrine system to regulate blood pressure during a sympathetic surge. [3 marks]
(c)
The researcher concludes: "The observed bradycardia is entirely due to the baroreceptor reflex acting above the lesion, and not due to direct spinal reflexes." Using the data and your knowledge of spinal cord anatomy, evaluate this conclusion. [2 marks]
diagram

Solutions

3ChallengeSAQ-LEndocrine and nervous system integration7 marksPaper 2~11 min
A researcher investigates the regulation of blood glucose concentration during moderate-intensity exercise. A healthy volunteer cycles at 70%70\% of maximal oxygen uptake for 30 minutes. Blood samples are taken at rest (0 min0\,\text{min}), during exercise (15 min15\,\text{min}), and after recovery (45 min45\,\text{min}). Variable — 0 min0\,\text{min} — 15 min15\,\text{min} — 45 min45\,\text{min} Plasma glucose (mmol L−1)(\text{mmol}\,\text{L}^{-1}) — 5.05.0 — 5.85.8 — 5.25.2 Plasma insulin (μU mL−1)(\mu\text{U}\,\text{mL}^{-1}) — 1212 — 66 — 1010 Plasma glucagon (pg mL−1)(\text{pg}\,\text{mL}^{-1}) — 8080 — 140140 — 9090 Plasma adrenaline (nmol L−1)(\text{nmol}\,\text{L}^{-1}) — 0.30.3 — 2.52.5 — 0.40.4 The pancreas contains alpha cells (secrete glucagon) and beta cells (secrete insulin). The sympathetic nervous system innervates the pancreas via splanchnic nerves.
(a)
Calculate the glucagon : insulin ratio at 0 min0\,\text{min} and at 15 min15\,\text{min}. [2 marks]
(b)
Explain how the sympathetic nervous system and the adrenal medulla act together on the pancreas to produce the hormonal changes observed between 0 min0\,\text{min} and 15 min15\,\text{min}. [3 marks]
(c)
Using the data and your answer to (a), evaluate the hypothesis that the rise in plasma glucose at 15 min15\,\text{min} is caused entirely by adrenaline acting on the liver, with no contribution from the change in the glucagon : insulin ratio. [2 marks]
diagram

Solutions

Questions 4-71

Unlock these questions with Premium

Sign Up →

That's every free question here — 3 of 71.

+68 more questions, plus Mock Papers & Worksheets, are waiting in Premium.

Upgrade