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MYP Biology: DNA, Genes & Chromosomes FAQ

Answered by RevisionPrep's IB Educators

DNA, genes and chromosomes trip up more MYP 4-5 students than any other genetics topic, mostly because the vocabulary looks similar but means very different things. Here's what I'd want a student or parent to know, straight from someone who's marked hundreds of these unit tests.

Understanding the Concept

What is the difference between DNA, a gene and a chromosome?

DNA is the molecule itself — a double helix of nucleotides. A gene is a specific section of that DNA coding for one protein or trait. A chromosome is a tightly coiled DNA molecule wrapped around proteins, visible under a microscope during cell division. Think: molecule, instruction, package.

Quick tip: if a question asks you to define one of these three, always compare it to the other two — examiners reward that you understand the hierarchy, not just the isolated definition.

Hierarchy: DNA → gene (a section of DNA) → chromosome (many genes coiled together) → nucleus (stores chromosomes).

How many chromosomes do humans have and why does it matter?

Humans have 46 chromosomes arranged in 23 pairs — one set of 23 from each parent. It matters because this pairing is exactly how MYP Biology explains inheritance: one allele per gene comes from each parent, which is why offspring share traits with both.

One pair (the 23rd) is the sex chromosomes — XX or XY. A common exam slip is writing '46 pairs' instead of '23 pairs of 46 total' — examiners do dock marks for that.

What is the difference between an allele and a gene?

A gene is the section of DNA controlling a particular trait, like eye colour. An allele is one specific version of that gene — brown or blue, for example. Every gene can have two or more alleles; you inherit one allele per gene from each parent.

Worked example: the gene for pea plant height has two alleles — T (tall) and t (short). A plant with genotype Tt carries both alleles for that one gene.

What is the difference between genotype and phenotype?

Genotype is the genetic makeup — the actual alleles an organism carries, like Tt. Phenotype is the observable result — what you actually see, like a tall plant. Two organisms can share a phenotype (tall) while having different genotypes (TT or Tt).

Worked example: for pea height, TT and Tt both give a tall phenotype because T is dominant. Only tt gives the short phenotype. This is exactly why a Punnett square predicts genotype ratios, but you then have to work out the phenotype ratio separately.

How do you work out a Punnett square for a monohybrid cross?

Cross two parents' alleles in a 2x2 grid, one parent's alleles along the top, the other's down the side, then fill in each box with the combined pair. Count the resulting genotypes and phenotypes to get your ratio — usually asked as 3:1 or 1:2:1.

  1. Write both parents' genotypes, e.g. Tt x Tt.
  2. Split each into single alleles: T, t and T, t.
  3. Draw a 2x2 grid and cross each combination.
  4. Read off results: 1 TT, 2 Tt, 1 tt.
  5. Convert to phenotype: 3 tall, 1 short (3:1 ratio) since T is dominant.

Common mistake: forgetting that Tt and tT are the same genotype — students sometimes count them as four different outcomes instead of grouping the heterozygotes together.

How MYP Assesses This Topic

How is DNA, genes & chromosomes assessed in MYP Biology?

It's assessed mainly under MYP Sciences Criterion A (Knowing and Understanding) and Criterion D (Reflecting on the Impacts of Science), using command terms like define, explain and outline. You'll typically meet it through unit tests, a genetics investigation, or an inquiry into inherited disorders, marked against the official MYP achievement level descriptors 1-8.

According to the IB's MYP: Sciences guide, Criterion A tasks assess recall and application of scientific knowledge (terminology, models, ratios from crosses), while Criterion D often asks you to evaluate implications — for instance, genetic screening or inherited disease. Schools usually assess this unit through a mix of short-answer tests and one extended task.

What command terms come up most in genetics questions?

The three you'll see constantly are define, describe and explain — each demands a different depth of answer. Define wants a precise, concise statement of meaning. Describe wants detail without reasoning. Explain wants you to give reasons or a cause-and-effect chain, which is where most marks get lost.

Command termWhat it wantsCommon student error
DefineExact meaning, no extra detailAdding examples that aren't asked for
DescribeDetailed account, no reasoningExplaining 'why' when only 'what' is needed
ExplainReasoning/cause and effectJust describing instead of justifying

What kind of exam questions come up on this topic?

Expect a mix: define/describe/explain short-answer questions on terminology, a Punnett square calculation with a genotype/phenotype ratio to interpret, and a data-response or extended question linking genetics to a real scenario like inherited disorders or selective breeding.

A typical unit test might allocate around 8-12 marks to terminology and Punnett squares combined, then 4-6 marks to a Criterion D-style question asking you to evaluate an ethical or societal issue linked to genetics — genetic testing is a favourite.

Common Mistakes & Study Strategy

What are the most common mistakes students make with this topic?

The biggest one, hands down: confusing dominant with 'more common' or 'stronger'. Dominant just means it's expressed when present — it has nothing to do with frequency in a population. Close behind: mixing up genotype and phenotype, and miscounting chromosome pairs.

Three to check before your next test:

  1. Can you explain dominant without using the word 'strong' or 'better'?
  2. Do you know the difference between homozygous and heterozygous, and can you spot both in a genotype like Tt or TT?
  3. Can you correctly state that humans have 23 pairs (46 total), not 46 pairs?

How do I actually revise DNA, genes and chromosomes for MYP Biology?

Start with the vocabulary hierarchy — DNA, gene, allele, chromosome — before touching Punnett squares; genetics falls apart fast if the terms are shaky. Then practise crosses until the 3:1 ratio feels automatic, and finish with a past-paper-style Criterion D question on a real genetic issue.

In my experience teaching this unit, students who skip straight to Punnett squares without nailing the vocabulary first are the ones who lose easy Criterion A marks later — they can do the maths but can't explain what a heterozygous genotype actually is when asked directly.

RevisionPrep's Topical Worksheets and Revision Notes on genetics on revisionprep.com are built around this exact sequence — terminology first, then application, then evaluation.

Why does my child find genetics harder than other MYP Biology topics?

Genetics is more abstract than cells or ecosystems — your child can't observe a gene directly, only its effects, so it demands stronger reasoning rather than memorisation. It's also the first MYP topic combining vocabulary, a mathematical skill (Punnett squares) and ethical evaluation in one unit, which is a lot to juggle at once.

This is exactly the kind of topic where structured worksheets help more than re-reading notes — practising the same cross with different alleles builds the pattern recognition that a single explanation in class often doesn't.

Looking Ahead & Resources

How does MYP genetics connect to DP Biology later?

MYP genetics is the groundwork for DP Biology's genetics topic, where Mendelian crosses expand into dihybrid crosses, pedigree analysis and molecular detail like meiosis and mutation. According to the IB, DP Biology's current syllabus (first exams 2025) builds directly on the allele/genotype/phenotype vocabulary introduced at MYP level.

Students who go into DP Biology HL or SL without a solid grip on genotype vs phenotype from MYP 4-5 often struggle with the added complexity of linked genes and codominance — it's worth getting this foundation right now rather than patching it later.

What resources actually help with this MYP Biology topic?

Look for materials that separate terminology practice from calculation practice from evaluation practice, rather than mixing all three at once — that's how the unit is actually assessed. Topical worksheets with mark schemes let a student self-check against real achievement-level descriptors, which is more useful than a textbook summary alone.

On revisionprep.com, the MYP Biology Revision Notes cover the terminology and worked Punnett square examples, while the Topical Worksheets give exam-style practice across Criterion A and D — useful for building both recall and evaluation skills before a unit test.

Key Genetics Terms Compared

TermWhat it meansExample
DNAThe molecule carrying genetic codeDouble helix in the nucleus
GeneA section of DNA for one traitGene for eye colour
AlleleOne version of a geneBrown or blue allele
ChromosomeCoiled DNA package23 pairs in humans
GenotypeGenetic makeup (alleles)Tt
PhenotypeObservable traitTall plant

For structured practice on this exact unit, see the MYP Biology Revision Notes and Topical Worksheets on revisionprep.com, built around Criterion A and D command terms.

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